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Any active malignancy is an absolute contraindication History of certain cancers: Discuss any cancer history with your physician

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Although insulin promotes glucose transport by signaling the phosphorylation of targets involved in vesicle tethering, docking, and fusion, its contribution to whole-body glucose disposal is comparatively minor [25]

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In contrast, M2-type macrophages demonstrate enhanced iron efflux capacity through higher ferroportin (FPN) expression and lower FT levels, inducing elevated CD91 or CD163 expression (79)

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