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This review provides an overview of how the defensive mucus of the airways functions in health, how the mucus can fail to clear with muco-obstructive lung diseases, how mucins respond to pathogens that infect the mucus, how the molecular signals of mucin secretion function, and how therapeutics may improve morbidity and mortality for people with muco-obstructive lung disease

( D ) The histograms show the percentages of pS6 + cells in IgD + B cells upon stimulation with gp34 1-179 , gp34 1-179W65F or -BCR

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