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While our nested casecontrol design, PSM analyses, dynamic PDC-based exposure assessment, and subgroup analyses help mitigate these concerns, they cannot fully eliminate them

10.1016/j.dsx.2020.04.031 186 MoshawihS.MydinR

Diabetes Care 40 , 136154 (2017)

Interestingly enough, in 6-OHDA rats, the dual GLP-1/GIP agonist (DA5-CH), in addition to promoting the survival of dopaminergic neurons, was able to reduce the levels of monomer and oligomers of -synuclein, thus providing a wider neuroprotective effect [53]

The MHRA monitors these medications closely and provides regular safety updates