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This initial period is not primarily for significant weight loss

It helps maintain arterial flexibility, contributing to vascular health

Furthermore, the transcription factor Nrf2, a master regulator of cellular antioxidant responses and iron/lipid metabolism, counteracts 6-hydroxydopamine-induced ferroptosis upon activation, highlighting its therapeutic potential (38, 39)

If you notice any new heart symptoms or feel that something is not right when on levothyroxine, it is a good idea to talk to your healthcare provider as soon as you can

Although there is limited current RCT data, a nested casecontrol study revealed a significant decrease in new-onset AF 1 year after HF hospitalization for patients with HFpEF [41]