Researchers from the Case Western Reserve University School of Medicine in Cleveland, Ohio, looked at three years of electronic medical records of almost over 1 million patients with type 2 diabetes, including those prescribed semaglutide, who had never been diagnosed with Alzheimer's disease and had at least one other cardiometabolic risk factor such as obesity, high blood pressure, elevated cholesterol, chronic kidney disease or history of stroke
Split dosing may help if: single morning dose produces effects that fade by afternoon, you are using higher doses (450-500mcg) where sustained levels may help, or evening administration fits your schedule better than early morning
The mean age was 55.8, 60% of participants were cis-male, there was no trans or non-binary representation and 91% were white
Intravenous 73 15.5
For the first seven days after the start of treatment, and three times a week thereafter, serum was collected for PK analysis and BG was measured ( Figure 4A )
GLP-1GLP-1GLP-1 3
