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doi: 10.1016/j.cmet.2022.11.013 80 ChengCGengFLiZZhongYWangHChengXet al

(A-B) Expression of (A-A) sima and (B-B) Ldh was measured in hemocytes of 3rd instar OXPHOS knockdown (GD library) female and male larvae and is shown here normalized to the expression of the control gene His3.3B expression, and relative to the gene expression level in the hemocytes of control animals

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Conversely, the NICE (2015) guidance gave a more limited choice after metformin and put the GLP-1 analogue class as a clear fourth-line option

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