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The nuclear and mitochondrial sirtuins, Sirt6 and Sirt3, regulate each others activity and protect the heart from developing obesity-mediated diabetic cardiomyopathy

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doi: 10.4103/0378-6323.116733 [DOI] [PubMed] [Google Scholar] 56.Saxena S, Gautam RK, Gupta A, Chitkara A

But this alone does not explain the specificity of the gene expression changes