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Carbon monoxide has a higher affinity to hemoglobin than oxygen, forming carboxyhemoglobin (COHb)

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"Some of the side effects we found, like nausea, are well known, and that shows that the method is picking up a real signal," says Sharath Chandra Guntuku, Research Associate Professor in Computer and Information Science (CIS) at Penn Engineering and the study's senior author

The observed reduction in HbA1c confirms the expected glycemic benefit of GLP-1 agonists, consistent with previous large-scale trials [16]