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Oxidative stress Oxidative stress is defined as an imbalance between free radicals and antioxidant defence systems (such as an overproduction of free radicals or a depletion of the bodys endogenous antioxidant defence systems)

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The OB GLP-1R-induced decrease in sympathetic nerve activity is GABA-dependent and relays via the PVN We next aimed to identify the mechanisms leading to the decrease in SNS activity after activation of the GLP-1R in the OB, which was confirmed by the observed increase in cFos expression in the MCL after local Ex4 injection (Fig