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In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in the patients treated with semaglutide injection (3%) compared to placebo (1.8%)

Although compounded drugs are permitted to be prescribed under federal law, they are not FDA-approved and do not undergo safety, effectiveness, or manufacturing review

For research protocol design purposes, this suggests that 48 weeks may be an insufficient observation window to capture the full weight loss potential of retatrutide at the 12mg dose

This doesnt mean that the neurons were asleep and are now awakened

Even sealed vials benefit from stopper cleaning before needle insertion

Sobczyska-Malefora A, Delvin E, McCaddon A et al