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The Stephens Group acknowledge Randles important work in their elaboration of the results of their own study stating In support of [Randles description] muscle long-chain acyl-CoA content returned to basal overnight during the L-carnitine infusion visit (whereas it remained suppressed during the control visit), which suggests that Beta-oxidation was indeed increasedwhile there was a 30% decrease in muscle PDC activity It is well established that there is a lag in oxidative ATP delivery at the onset of exercise and muscular contraction