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Hence, the upregulation of the thiamine/ThDP-dependent protein transcripts 69 months after gastric bypass (Figures 4B, 5B) maybe a biochemical indicator of thiamine insufficiency in the enterocytes

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These metabolic improvements occurred alongside increased phosphorylation of insulin receptor substrate and Akt, key signaling molecules in the insulin/IGF-1 pathway

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Studies evaluating the impact of periodontal disease on quality of life and the use of oral supplements in managing musculoskeletal conditions highlight the potential importance of this area of research [141]

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