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In human research of chronic insomniacs DSIP had normalizing influence on sleep regulation

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The peptide's biological activity in research models depends on its 1:1 chelation of a copper(II) ion

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Some patients experience nausea, constipation, or vomiting

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The leukotriene B(4)/BLT1-dependent neutrophil accumulation exacerbates immune complex-mediated glomerulonephritis

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