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Serious adverse events in tirzepatide trials remain rare

This disparity is hypothesized to arise from differences in estrogen-mediated neuroprotection, lifestyle factors, and occupational exposure to neurotoxins (Ben-Shlomo et al., 2024) (Figure 2)

Human chorionic gonadotropin (hCG) mimics the action of luteinizing hormone (LH), directly stimulating Leydig cells in the testes to continue producing intratesticular testosterone

doi: 10.1136/bmj.d7771 29 GersteinHCColhounHMDagenaisGRDiazRLakshmananMPaisPet al