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Mechanical allodynia and thermal hyperalgesia were evaluated in separate experiments in a time-dependent manner

It slows gastric emptying (how quickly food leaves the stomach) and causes gut distension (an enlargement of the gut)

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Despite this, with improper storage the molecule can undergo gradual aggregation

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Taken together, for rapid and precise detection and/or treatment of APAP-associated idiosyncratic DILI, it is necessary to assess the causality by the RUCAM score