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[1] [2] Individual gastrointestinal sensitivity: Patients with pre-existing gastrointestinal conditions such as gastroparesis, irritable bowel syndrome, or functional dyspepsia may experience earlier and more severe symptoms

Pharmacokinetics of caffeine following a single administration of coffee enema versus oral coffee consumption in healthy male subjects

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However, compared with previous reviews (4,16,18), the present study distinguishes itself by offering an in-depth examination of oxidative stress in endometriosis, focusing on the disruption of oxidative balance and the increased production of ROS resulting from mitochondrial dysfunction and abnormal iron metabolism