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Science (1992) 256(5064):167780.10.1126/science.256.5064.1677 46 RowlinsonSWBehnckenSNRowlandJEClarksonRWStrasburgerCJWuZet alActivation of chimeric and full-length growth hormone receptors by growth hormone receptor monoclonal antibodies

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This study suggests that IGF-1 may play a role in promoting collagen production in humans, but neither provides any direct proof for a causative effect nor is it able to identify whether IGF-I or rather GH is the regulating factor for collagen synthesis in human tendons

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