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From this cohort, 45 women [15 without mood disorders and 30 with mood disorders (Major depression and Bipolar disorder)] were selected at 18 months postpartum, the depression and suicide risk were assessed using the Mini-International Neuropsychiatric Interview Plus (MINI-Plus) instrument, module A and C, respectively

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Severe gastrointestinal symptoms could also lead to dehydration, which may increase the risk of methotrexate toxicity by affecting renal function

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