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Phytochemistry 9 (2), 409414

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Similarly, in vitro exposure of macrophages to 10 M of ACh prior to endotoxin challenge reduces TNF- production by increasing adenylyl cyclase 6 activity, leading to cAMP formation, CREB phosphorylation, and the expression of c-Fos, a known inhibitor of TNF transcription (85)

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Additionally, GLP-1 promotes the growth and proliferation of pancreatic cells, inhibits glucagon secretion, and enhances peripheral tissue uptake of glucose, making it a key factor in maintaining stable blood glucose levels