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Both pathways can be medically appropriate depending on patient access, cost, provider preference, and clinical context

The idea is plausible mechanistically

Published Research on 5-Amino-1MQ Foundational DIO Mouse Study Neelakantan et al., Biochemical Pharmacology (2018) This paper introduced 5-Amino-1MQ as a selective and membrane-permeable small molecule inhibitor of NNMT and tested it in 3T3-L1 adipocytes and in male C57BL/6J mice maintained on a high-fat diet

Genisel M, Erdal S, Kizilkaya M (2015) The mitigating effect of cysteine on growth inhibition in salt-stressed barley seeds is related to its own reducing capacity rather than its effects on antioxidant system

11 probiotic strains + 5 enzymes gentle on a sensitive gut