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They are often related to dehydration, reduced caloric intake, or caffeine withdrawal if coffee consumption decreases alongside overall food intake

[2] The problem is that those results are almost entirely from animals

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lag-2(q411) strains and assayed the penetrance of rescue by picking 10-15 egg-laying adult P0s onto plates seeded with OP50, removing them after 3 hours of egg-laying, and then scoring progeny 24 hours later for developmental arrest