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Estn contraindicados en personas con historia de carcinoma medular de tiroides o sndrome MEN2, y requieren monitoreo para pancreatitis y complicaciones biliares
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doi: 10.1016/j.cmet.2024.10.003 198 TongX.DongJ
Plasma membrane diffusion assay by Raster imaging correlation spectroscopy (RICS) INS-1 832/3 GLP-1R KO cells were transfected with 0.5 g WT or triple AA phospho-null mutant SNAP/FLAG-hGLP-1R constructs before seeding onto 35-mm glass-bottom dishes (MatTek Corporation) and labelling with membrane-impermeable SNAP-Surface Alexa Fluor 647 probe (S9136S, New England Biolabs) for 12 minutes at 37C in complete media
In most cases, the more important factor appears to be the patients underlying metabolic health rather than the medication itself
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