One of the limitations of our study is that we measured expression levels on transcriptional level only and the activity and quantity of the studied enzymes was not evaluated.
In one embodiment the concentration of HEC is between about 1% and about 15%, about 1% and about 2%, or about 1.5% to about 2%
While generally safe and effective, individual responses to medication can vary
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Patients with PCOS may experience: reproductive abnormalities inflammation correlated with insulin resistance irregular or absent menstrual periods excess androgens (male hormones such as testosterone) polycystic ovaries resulting from the hormonal imbalances hirsutism (male-patterned hair growth) acne alopecia (thinning or loss of scalp hair) Additionally, both reproductive-age and older women with PCOS have an increased risk for conditions such as: impaired glucose tolerance type 2 diabetes mellitus elevated cholesterol or lipids increased abdominal adiposity obesity hypertension metabolic syndrome depression anxiety obstructive sleep apnea nonalcoholic fatty liver disease endometrial cancer cardiovascular disease Research suggests that medication alone might not be enough to address PCOS
GraphPad Prism 9 software (GraphPad Software, San Diego, CA, USA) was used for statistical analyses
