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Tesamorelin + Ipamorelin Side Effects & Safety Compound-level safety From tesamorelin trials, the most commonly reported adverse events include injection-site reactions (redness, itching), joint pain (arthralgia), pain in the extremities, peripheral edema (fluid retention), and muscle aches

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doi: 10.1080/10715760500072172

However, the ligand-binding pocket exhibited two unique structural features that were not observed in previously determined GPCRs