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Questions regarding the cardiovascular safety of drugs prescribed for T2DM arose as individuals treated with sulfonylureas and insulin showed an increased incidence of major adverse cardiovascular events (MACEs: death from cardiovascular causes, nonfatal myocardial infarction, or nonfatal stroke) [18, 19]

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J Affect Disord 15(369):922927 [DOI] [PubMed] [Google Scholar] 84.Schoretsanitis G, Weiler S, Barbui C, Raschi E, Gastaldon C (2024) Disproportionality Analysis From World Health Organization Data on Semaglutide, Liraglutide, and Suicidality

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Semaglutide Half-Life: Why Weekly Dosing Makes Sense Semaglutide's approximately 7-day half-life aligns perfectly with once-weekly injection schedules