Riboflavin is also a component of the glutathione redox cycle 24 , and lower riboflavin levels may lead to reduced glutathione
The nutrient can thus exert its effect for a longer period
As a result, the study provided useful information for enhancing the safety and efficacy of isotretinoin treatment, as well as lowering isotretinoin-related side effects
J Am Heart Assoc 4:e001469
Lancet 359:20532058 Belch J, Hiatt WR, Baumgartner I, Driver IV, Nikol S, Norgren L, Van Belle E, Committees T, Investigators (2011) Effect of fibroblast growth factor NV1FGF on amputation and death: a randomised placebo-controlled trial of gene therapy in critical limb ischaemia
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