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It remains under clinical investigation and has not yet received regulatory approval from the Medicines and Healthcare products Regulatory Agency (MHRA) or the European Medicines Agency (EMA)

Resistance training also improves insulin sensitivity independent of weight loss, which supports better metabolic function and may complement GLP-1 receptor resensitization

Patients were allowed to increase the insulin dose only up to the starting insulin dose prior to randomization

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I didnt get much traction on detailed pharmacy questions, but they were otherwise helpful

Hypoglycemia The use of pramlintide with insulin has been associated with an increased risk of insulin-induced severe hypoglycemia in both T1D and T2D