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Researchers have spent years studying how changes to amylin may influence biological activity, receptor interactions, and pharmacokinetic characteristics

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While therapeutic drug monitoring (TDM) is essential to prevent underexposure associated with increased rejection risk, and overexposure, which leads to an increase in adverse events, it has limitations in predicting the required Tac dose, due to the many factors that impact the Tac metabolism (12)

Receptor gene expression of glucagon-like peptide-1, but not glucose-dependent insulinotropic polypeptide, in rat nodose ganglion cells

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