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The mechanisms of the beneficial activity of curcumin on the nervous system include limiting the production of ROS and reactive nitrogen species (RNS), and counteracting the decreased activity (SOD) and level (GSH) of antioxidants [65]

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Additionally, age-related changes include an increase in fat mass, a decline in basal metabolic rate (2%3% per decade), and a decrease in bone mineral density (1%3%/year) (Keys et al., 1973

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