Several RCT investigated the role of liraglutide, alone or in combination with metformin, in women with PCOS and overweight or obesity, confirming its beneficial effect on anthropometric and metabolic features 95
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Wegovy is also manufactured by Novo Nordisk
There was also an association with pre-operative gastrointestinal symptoms (e.g., nausea, vomiting, abdominal pain, bloating) and the degree of residual gastric contents
Its triple agonism, including glucagon receptor activation, distinguishes it from dual-agonist tirzepatide and may provide enhanced energy expenditure and hepatic fat reduction
