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Severe nausea requiring medication discontinuation occurs in about 3 to 7 percent of patients with both formulations

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Conclusion on Glutathione and Fasting Based on the current understanding, taking glutathione in its pure form, especially in a low-calorie or non-insulinogenic format, is unlikely to break a fast

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doi: 10.1002/ptr.v23:3 121 FDA

That being said, both medications are considered safe for most individuals when used under the supervision of a healthcare provider