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How often should thalassemia patients be tested for B12 deficiency
M2 macrophages exhibit angiogenic and proinvasive properties, producing growth factors, chemokines, and MMPs that stimulate tumor growth, invasion, and metastasis (93), particularly facilitating tumor cell extravasation and growth in secondary sites
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The key detoxication enzyme is MerA, the mercuric ion reductase, and also a second enzyme, MerB, is present in the gene cassette, and its activity is to split the carbon-Hg bond in organomercurials such as the potent, naturally occurring neurotoxic agent methylmercury chloride and the synthetic chemical disinfectant phenylmercuric acetate [89,90,91]
