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It has a good safety profile and is allowed to be used at a max concentration of 5% both in the US and in Europe (10% is allowed in Japan)
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In addition, HFD also promotes apoptotic processes at the hypothalamic level 62 , and weight-lowering therapies, as exercise, contribute to mitigate apoptosis in hypothalamic neurons 60
Competing interests None of the authors have any conflict of interests
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While they are increasingly popular for addressing various skin concerns, it's crucial to prioritize safety and consultation with a qualified dermatologist or skincare expert
