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Moreover, the abundance of bacteria carrying bile salt hydrolase and bile acid inducible enzyme in the gut microbiota of IBD patients, such as Firmicutes , Ruminococcaceae , Lachnospiraceae , and Eubacterium , is reduced

For MOTS-c, research protocols discussed in investigational contexts vary widely, but often involve subcutaneous administration of 5-15 mg, 2-3 times weekly

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All reactions were run in triplicate for at least three independent experiments

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