Other common effects include vomiting, diarrhea, abdominal pain, and constipation
SURMOUNT-5: Tirzepatide vs Semaglutide for Obesity
The trade-off is increased complexity, cost, two separate injections, and additional side effect management
Notably, it is a non-peptide, once-daily pill that can be taken without regard to food or water, marking an incremental but meaningful shift for a class long defined by injectables and more restrictive dosing requirements
for example, semaglutide (injectable) or tirzepatide (injectable) are not oral
# A non-parsimonious PS model was used to alleviate the effect of potential confounding on systematic differences in patient characteristics based on treatment exposure