Individuals with polymorphisms in these genes may have altered Se metabolism and, consequently, variable responses to supplementation
In a study published in the New England Journal of Medicine, individuals who received semaglutide for 68 weeks lost an average of 15.3% of their body weight, compared to 2.6% in the placebo group
Perhaps even more intriguing, those in the placebo-controlled trials taking topiramate didnt plateau during the study, suggesting the weight management benefits would continue (though it may mean taking the medication for an extended period of time to get the maximum results)
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doi:10.4103/jhrs.JHRS_74_16 Vijayakumar A, Kim EK, Kim H, Choi YJ, Huh KB, Chang N
& Taylor, F
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