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Further investigations showed no indication that the cleavage sites for the destabilized hybrids were located in or next to the oligourea triads making it more puzzling

So GHRH(1-29) is essentially the minimal sequence needed for the receptor agonism mechanism

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[12] Some medications, such as aprepitant, are chemically modified to be better suited for IV administration, forming a prodrug such as fosaprepitant

GSH-dependent activation releases Cu + to engage lipoylated DLAT and simultaneously unmasks glucose oxidase activity, inducing nutrient deprivation and triggering cuproptosis 216

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