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Recently, we used albumin knockout mice and demonstrated that a higher fraction of OTA passes from the blood into hepatocytes and renal tubular epithelial cells resulting in increased levels of toxicity in hypoalbuminemic compared to wild-type mice (Hassan et al
IPR003115) but that lacked the strictly conserved SRX-N terminal binding motif F ( S / G ) GCHR required for catalytic activity (Supplementary file 1, Table S4)
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Kisspeptin A peptide involved in reproductive hormone signaling and hormonal regulation