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Consequently, it attracts growing interest across regenerative medicine and musculoskeletal research disciplines

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(2004) Proc Natl Acad Sci U S A 101 : 13163 PubMed: 15333749 Search on PubMedSearch on PubMed Central DOI: Primary Citation Related Structures: 1USB PubMed Abstract: A strategy for rational enzyme design is reported and illustrated by the engineering of a protein catalyst for thiol-ester hydrolysis

6.1 Diabetes Type I diabetes, Type II DM, and gestational diabetes are characterized by hyperglycemia, dyslipidemia, and insulin resistance, which increase oxidative stress and activate the protein kinase C (PKC) as well as the receptor for advanced product glycation (AGE) and low levels of antioxidants and GPx in diabetic patients