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Once reconstituted, the solution should be used promptly or aliquoted and stored at -20C to avoid repeated freeze-thaw cycles, which can degrade the compound

It enhances VEGF-stimulated angiogenesis and attenuates effects of chronic hypoxia [105]

The reason for the toxicity order is attributed to the decrease of the concentration of Zn 2+ ions by the generation of precipitates and zinc complexes in different media

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