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Karshya karshnya usha kaamithva kampa anaha sakrtgrhaan // (Ashtangahridaya, Sutra Sthana, Chapter 11) Bala varna sukha ayushman upaghataya, mano vyaharshayati // (Caraka Samhita, Sutra Sthana, Chapter 12, Sloka 6) Emaciation, blackish pigmentation, longing for hot, tremors, bloating and constipation are the main features of aggravated vata

A common source of ethical controversy lies in the concept of therapeutic misconception (where people volunteer to participate believing that they will be guaranteed results, when in fact results and safety are not guaranteed in any trial.) Balancing this optimism is essential for trial runners while they need to keep their participants hopeful and engaged in the process, they also need to outline the expectations and potential risks of the trial

doi: 10.1016/j.bbalip.2012.07.011 120 BoleGG

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