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The evidence from both animal and human studies suggests that melatonin has significant potential as a therapeutic agent for improving cognitive function and mitigating cognitive impairments associated with AD

FIGURE 1 3.4 Sensitivity analysis: effects of bioavailability improvements and dosing frequency A legitimate question arises: could modest improvements in bioavailability or modified dosing strategies overcome the half-life constraint

10.1016/j.jocn.2020.09.054 28 ChecaJ.AranJ

Cytotoxic compounds linked to analogs of hormonal peptides like LHRH, bombesin, and somatostatin can be targeted to certain tumors possessing receptors for those peptides and therefore are more selective for killing cancer cells [89, 90]