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Seleniums antioxidant capabilities and function in promoting the activity of antioxidant enzymes may have implications for lowering oxidative stress, even though there is little direct study on its impact on adrenal hormone imbalance-related oxidative stress (136)

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Reduces markers of cellular damage and free radical formation

CNIs exhibit their immunosuppressive properties by inhibiting the cytoplasmic dephosphorylation of NFAT (nuclear factor of activated T-lymphocytes), thereby preventing it from entering the cell nucleus and triggering downstream cytokine production

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These conjugates are more water-soluble and can be efficiently eliminated from the body via the liver and kidneys