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PCD represents a special category of regulated cell death (RCD), which is a more broadly defined category as a cell demise occurring in an orderly fashion through a well-coordinated genetically encoded machinery in response to a wide spectrum of internal and external perturbations [2]

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While side effects for both forms are generally mild and transient, individuals need to monitor their responses and consult healthcare providers if they experience any severe or persistent issues

When utilised in conjunction with liposomes, chemical enhancers such as ethanol, oleic acid, terpenes, and surfactants interact synergistically to augment the permeability of both the skin and the liposomal vesicles

Furthermore, CaT-ME facilitated dermal thickening of the skin in mice, as assessed via H&E and Masson staining (Fig