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Back Unger, RH, Ketterer, H Dupr, J, Eisentraut, I (1967) 'The effects of secretin, pancreozymin, and gastrin on insulin and glucagon secretion in anesthetized dogs', Journal Clinical Investigation , 46/4, 63045

It showed unprecedented weight reductions of up to 28.3% to 28.7% (approximately 70 lbs) and significant A1C decreases

In obese individuals, arguably thats not the end of the world because its almost a training response to moving a large body around

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The increasing effectiveness and adoption of GLP-1RAs for obesity management are catalyzing a paradigm shift in both public and professional attitudes toward obesity