Although BPTES and V-9302 treatment can promote M1 macrophage polarization or enhance CD8 + T cell anti-tumor function, they have also been found to enhance the expression of PD-L1 on tumor cells (Liu et al., 2017
Studies have examined its interaction with growth factor pathways, particularly the FAK-paxillin signaling cascade, which plays a role in cell migration and tissue remodeling
"Senolytics in idiopathic pulmonary fibrosis: Results from a first-in-human, open-label, pilot study"
Reducing the number of laboratory animals used in tissue engineering research by restricting the variety of animal models
maintaining a balance in health and disease
Biochim Biophys Acta 1864:13151321 Lallement PA, Meux E, Gualberto JM, Dumarcay S, Favier F, Didierjean C, Saul F, Haouz A, Morel-Rouhier M, Gelhaye E, Rouhier N, Hecker A (2015) Glutathionyl-hydroquinone reductases from poplar are plastidial proteins that deglutathionylate both reduced and oxidized glutathionylated quinones