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The endogenous sources of oxidants include cellular systems localized on the plasma membrane, in the cytosol, in the peroxisomes, and on membranes of mitochondria and endoplasmic reticulum

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Glucagon like peptide-1 (GLP-1) is a hormone secreted by intestinal L cells, which reacts to nutrients and plays a glucose dependent insulin promoting role in pancreatic islet cells

210,211 Mechanistically, IRF8 binds interferon-stimulated response elements in the promoters of key ATGs, including ATG5, ATG7, MAP1LC3B , and BECN1 , thereby increasing autophagosome formation

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2026 Jan 28 [cited 2026 Feb 1];25(2):e706922