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6,12-14 The RE-LY trial was a multicenter, randomized, controlled trial that compared 2 regimens of dabigatran, 110 mg twice daily and 150 mg twice daily, with dose-adjusted warfarin

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The endothelial solute CMT facilitates the crossing of specific solutes across the BBB via substrate-specific transporters, with docosahexaenoic acid (DHA) being transported by major facilitator superfamily domain containing 2a (Mfsd2a) and glucose by glucose transporter 1 (Glut1), ensuring targeted delivery of these vital nutrients to the brain [19, 24,25,26,27]