The synergistic metabolic benefits of pharmacological modulation of GLP-1, GIP, and glucagon receptors were first demonstrated in 2015
As we previously published, a multiweapon approach is needed to successfully combat SARS-CoV-2 and COVID-19 disease (Labarrere and Kassab, 2021), involving vaccines (Jin et al., 2022) especially vaccines that selectively and efficiently induce antibodies that target the SARS-CoV-2 receptor binding domain (Robbiani et al., 2020), pattern recognition proteins such as surfactant proteins A and D (Arroyo et al., 2021
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Consequently, subclinical vitamin D deficiency is highly prevalent in both urban and rural settings, and across all socioeconomic and geographic strata as was seen in our patient.[9] The role of this hypovitaminosis D-induced hypophosphtemia may also have contributed to severity of hemolysis as effect of hypophosphatemia causing hemolysis is well known.[10] However, the levels of serum phosphorus may sometimes be normal or even spuriously increased in cases of severe hemolysis due to leakage of phosphorus from the RBCs[10] So concurrent presence of such deficiencies should be looked for and corrected for timely recovery