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Switching was defined as a change to a different GLP-1 between consecutive months (e.g., January to February 2025)

According to the World Health Organization, obesity prevalence has nearly tripled since 1975, and it is associated with increased risks of developing chronic diseases such as type 2 diabetes, cardiovascular disease, and certain types of cancer

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O ensaio incluiu pessoas sem diabetes, com IMC mdio de 40,4kg/m, e ambas as doses atingiram todos os desfechos primrios e secundrios: reduo de peso, diminuio da dor (at 75,8% de reduo no escore de dor WOMAC) e melhora da funo fsica

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